Preliminary studies in our laboratory have demonstrated the importance of both the NH2 and COOH terminus scaffolding functions of focal adhesion kinase (FAK) These results highlight the underlying importance of targeting the FAK scaffold to treat human cancers.

The management of small pancreatic cystic lesions presents a clinical challenge. Initial conservative management of small cystic pancreatic lesions may be indicated in selected patients.

We evaluated PC-related treatment patterns and associated health care resource use among patients with metastatic PC in the United Kingdom and France. This study provides new, detailed information for patients with metastatic PC in real-world settings in 2 European countries. A small proportion of patients received >1 line of systemic therapy for metastatic disease, which is likely due to the aggressiveness of this disease and the lack of effective therapeutic options.

Link to: http://www.ncbi.nlm.nih.gov/pubmed/25907619

Pancreatic neoplasms have a wide range of pathology, from pancreatic adenocarcinoma to cystic mucinous neoplasms. Endoscopic ultrasound (EUS) with or without fine needle aspiration (FNA) is a helpful diagnostic tool in the work-up of pancreatic neoplasms. This review covers the technical aspects of optimizing pancreaticneoplasm diagnosis rate, highlight rare pancreatic neoplasms and role of EUS-FNA, and also outline the important factors in diagnosis of cystic lesions by EUS-FNA. 

Link to: http://www.ncbi.nlm.nih.gov/pubmed/25901210